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Inside of a latest review, we noted the identification and the characterization of a completely new atypical opioid receptor with one of a kind negative regulatory Homes towards opioid peptides.1 Our success confirmed that ACKR3/CXCR7, hitherto generally known as an atypical scavenger receptor for chemokines CXCL12 and CXCL11, is usually a wide-spe